Multiple extrauterine adenomyomas and uterus-like masses: case reports and review of the literature.
Fertil Steril
; 91(5): 1956.e9-11, 2009 May.
Article
in En
| MEDLINE
| ID: mdl-19254794
ABSTRACT
OBJECTIVE:
To describe two rare cases of multiple extrauterine adenomyomas, their clinical management, and their response to surgical and hormone therapy with GnRH agonist.DESIGN:
Case report and review of the English-language scientific literature.SETTING:
Cases presented in a tertiary health care academic institution. PATIENT(S) Two patients without urogenital malformations diagnosed with extrauterine adenomyoma, which is a benign tumor composed of smooth muscle and endometrium, typically originating within the uterus. INTERVENTION(S) Surgical radical excision of adenomyomas followed by a long-term hormone therapy with GnRH agonist. MAIN OUTCOME MEASURE(S) Anatomical and clinical outcomes. RESULT(S) Surgical treatment followed by long-term GnRH agonist therapy appeared effective in keeping the disease stable. After a long-term follow-up of 10 and 4 years, the two patients are still asymptomatic and stable. CONCLUSION(S) Only 19 other cases of extrauterine adenomyomas are reported in the English-language scientific literature, and no cases of multiple masses are described until now. It is probable that these extrauterine adenomyomas arose from a metaplastic transformation of the subcelomic mesenchyme. Long-term GnRH agonist therapy after surgery appeared effective in keeping the disease stable.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Uterus
/
Adenomyoma
/
Intestinal Neoplasms
Limits:
Adult
/
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Fertil Steril
Year:
2009
Document type:
Article
Affiliation country:
Italy