Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.

Crowley, Steven D; Vasievich, Matthew P; Ruiz, Phillip; Gould, Samantha K; Parsons, Kelly K; Pazmino, A Kathy; Facemire, Carie; Chen, Benny J; Kim, Hyung-Suk; Tran, Trinh T; Pisetsky, David S; Barisoni, Laura; Prieto-Carrasquero, Minolfa C; Jeansson, Marie; Foster, Mary H; Coffman, Thomas M

Crowley, Steven D; Vasievich, Matthew P; Ruiz, Phillip; Gould, Samantha K; Parsons, Kelly K; Pazmino, A Kathy; Facemire, Carie; Chen, Benny J; Kim, Hyung-Suk; Tran, Trinh T; Pisetsky, David S; Barisoni, Laura; Prieto-Carrasquero, Minolfa C; Jeansson, Marie; Foster, Mary H; Coffman, Thomas M.

Affiliation

Crowley SD; Department of Medicine, Division of Nephrology, Duke University Medical Center, and Durham VA Medical Center, Durham, North Carolina 27705, USA.

J Clin Invest ; 119(4): 943-53, 2009 Apr.

Article in En | MEDLINE | ID: mdl-19287096

Subject(s)

Autoimmune Diseases/etiology; Nephritis/etiology; Receptor, Angiotensin, Type 1/physiology; Animals; Autoimmune Diseases/immunology; Autoimmune Diseases/pathology; Autoimmune Diseases/physiopathology; Chemokines/genetics; Cytokines/genetics; Female; Kidney/injuries; Kidney/pathology; Kidney/physiopathology; Male; Mice; Mice, Inbred MRL lpr; Mice, Knockout; Nephritis/immunology; Nephritis/pathology; Nephritis/physiopathology; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptor, Angiotensin, Type 1/deficiency; Receptor, Angiotensin, Type 1/genetics; Renin-Angiotensin System/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autoimmune Diseases / Receptor, Angiotensin, Type 1 / Nephritis Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Clin Invest Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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