Discovery and exploitation of inhibitor-resistant aurora and polo kinase mutants for the analysis of mitotic networks.

Scutt, Paul J; Chu, Matthew L H; Sloane, Dominic A; Cherry, Mike; Bignell, Colin R; Williams, David H; Eyers, Patrick A

Scutt, Paul J; Chu, Matthew L H; Sloane, Dominic A; Cherry, Mike; Bignell, Colin R; Williams, David H; Eyers, Patrick A.

Affiliation

Scutt PJ; Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom.

J Biol Chem ; 284(23): 15880-93, 2009 Jun 05.

Article in En | MEDLINE | ID: mdl-19359241

Subject(s)

Protein Serine-Threonine Kinases/metabolism; Aurora Kinase B; Aurora Kinases; Benzamides; Binding Sites; DNA Mutational Analysis; DNA, Complementary; Enzyme Inhibitors/pharmacology; Humans; Imatinib Mesylate; Kinetics; Mitosis; Mutagenesis; Piperazines/pharmacology; Protein Serine-Threonine Kinases/antagonists & inhibitors; Protein Serine-Threonine Kinases/genetics; Pyrimidines/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Serine-Threonine Kinases Limits: Humans Language: En Journal: J Biol Chem Year: 2009 Document type: Article Affiliation country: United kingdom Country of publication: United States

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