Steroid treatments in mice do not alter the number and function of regulatory T cells, but amplify cyclophosphamide-induced autoimmune disease.

Moraes-Fontes, Maria Francisca; Rebelo, Manuel; Caramalho, Iris; Zelenay, Santiago; Bergman, Marie-Louise; Coutinho, António; Demengeot, Jocelyne

Moraes-Fontes, Maria Francisca; Rebelo, Manuel; Caramalho, Iris; Zelenay, Santiago; Bergman, Marie-Louise; Coutinho, António; Demengeot, Jocelyne.

Affiliation

Moraes-Fontes MF; Instituto Gulbenkian de Ciência, Rua da Quinta Grande 6, Oeiras, Portugal. mffontes@igc.gulbenkian.pt

J Autoimmun ; 33(2): 109-20, 2009 Sep.

Article in En | MEDLINE | ID: mdl-19362805

Subject(s)

Anti-Inflammatory Agents/adverse effects; Colitis/immunology; Encephalomyelitis, Autoimmune, Experimental/drug therapy; Hydrocortisone/adverse effects; T-Lymphocytes, Regulatory/drug effects; Adoptive Transfer; Animals; Anti-Inflammatory Agents/administration & dosage; CD4 Lymphocyte Count; Colitis/prevention & control; Cyclophosphamide/administration & dosage; Drug Therapy, Combination; Homeodomain Proteins/genetics; Homeodomain Proteins/immunology; Homeodomain Proteins/metabolism; Hydrocortisone/administration & dosage; Immunosuppressive Agents/administration & dosage; Lymphopenia/chemically induced; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; T-Lymphocytes, Regulatory/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hydrocortisone / T-Lymphocytes, Regulatory / Colitis / Encephalomyelitis, Autoimmune, Experimental / Anti-Inflammatory Agents Limits: Animals Language: En Journal: J Autoimmun Journal subject: ALERGIA E IMUNOLOGIA Year: 2009 Document type: Article Affiliation country: Portugal

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