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A study of aspirin resistance in type 2 diabetes.
Singla, Mani Kant; Lahiri, Prabir; Mukhopadhyay, Pradip; Pandit, Kaushik; Chaudhuri, Utpal; Chowdhury, Subhankar.
Affiliation
  • Singla MK; Department of Endocrinology, IPGME&R and SSKM Hospital, Kolkata.
J Indian Med Assoc ; 106(11): 720, 722-3, 740, 2008 Nov.
Article in En | MEDLINE | ID: mdl-19368097
ABSTRACT
Aspirin is currently known to give inadequate protection against coronary artery disease in diabetes compared to person without it. We evaluated 97 consecutive patients with type 2 diabetes for assessing laboratory aspirin resistance and attempted to assess the impact of various clinical and biochemical parameters on it. Thirty-eight patients (39.1%) were found to be less sensitive to the action of aspirin, 7 persons (7.2%) were found to be resistant and 31 persons (31.9%) were aspirin semi-responders. Only total cholesterol, LDL-cholesterol and triglyceride had statistically significant impact on aspirin resistance (p<0.05). Three persons out of 9 with some form of macrovascular disease had aspirin resistance.
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Collection: 01-internacional Database: MEDLINE Main subject: Coronary Artery Disease / Drug Resistance / Platelet Aggregation Inhibitors / Aspirin / Diabetic Angiopathies Type of study: Etiology_studies / Risk_factors_studies Limits: Humans / Middle aged Language: En Journal: J Indian Med Assoc Year: 2008 Document type: Article
Search on Google
Add to My VHL
Print
XML
PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Coronary Artery Disease / Drug Resistance / Platelet Aggregation Inhibitors / Aspirin / Diabetic Angiopathies Type of study: Etiology_studies / Risk_factors_studies Limits: Humans / Middle aged Language: En Journal: J Indian Med Assoc Year: 2008 Document type: Article