Itopride and pantoprazole outcomes in diabetic gastroparesis trial (IPOD trial).
J Indian Med Assoc
; 106(12): 814-5, 2008 Dec.
Article
in En
| MEDLINE
| ID: mdl-19370958
ABSTRACT
The most common cause of gastroparesis is diabetes mellitus. The present study was carried out to asses the combination of itopride and pantoprazole in the treatment of diabetic gastroparesis. The study was an open label, multicentre, conducted in 743 patients with diabetic gastroparesis for a period of 3 weeks. The efficacy parameters included nausea, vomiting, early satiety, bloating, postprandial fullness, epigastric pain and regurgitation. The patients were evaluated based on the frequency and severity of symptoms and compared with the baseline scores. There were significant improvement in severity as well as the frequency of all the symptom parameters of the disease (p<0.001). The physicians' evaluation to the therapy was rated either excellent or good.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Benzamides
/
Benzyl Compounds
/
Gastrointestinal Agents
/
Gastroparesis
/
Diabetes Complications
/
2-Pyridinylmethylsulfinylbenzimidazoles
/
Proton Pump Inhibitors
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
Limits:
Adolescent
/
Adult
/
Aged
/
Humans
/
Middle aged
Language:
En
Journal:
J Indian Med Assoc
Year:
2008
Document type:
Article