Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function.

Petrof, Elaine O; Claud, Erika C; Sun, Jun; Abramova, Tatiana; Guo, Yuee; Waypa, Tonya S; He, Shu-Mei; Nakagawa, Yasushi; Chang, Eugene B

Petrof, Elaine O; Claud, Erika C; Sun, Jun; Abramova, Tatiana; Guo, Yuee; Waypa, Tonya S; He, Shu-Mei; Nakagawa, Yasushi; Chang, Eugene B.

Affiliation

Petrof EO; Department of Medicine, GIDRU, Division of Infectious Diseases, Queen's University, Kingston, ON, Canada. eop@queensu.ca

Inflamm Bowel Dis ; 15(10): 1537-47, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19373789

Subject(s)

Culture Media, Conditioned/pharmacology; Intestinal Mucosa/metabolism; Lactobacillus plantarum; NF-kappa B/antagonists & inhibitors; Probiotics/pharmacology; Proteasome Inhibitors; Animals; Blotting, Western; Cells, Cultured; Chemokine CCL2/metabolism; Dendritic Cells/metabolism; Dendritic Cells/microbiology; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Female; Intestinal Mucosa/immunology; Intestinal Mucosa/microbiology; Intestines/immunology; Intestines/microbiology; Macrophages/metabolism; Macrophages/microbiology; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88/metabolism; NF-kappa B/metabolism; Proteasome Endopeptidase Complex/metabolism; Rats; Receptors, Tumor Necrosis Factor, Type I/metabolism; Receptors, Tumor Necrosis Factor, Type II/metabolism; Ubiquitin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Culture Media, Conditioned / Probiotics / Lactobacillus plantarum / Proteasome Inhibitors / Intestinal Mucosa Limits: Animals Language: En Journal: Inflamm Bowel Dis Journal subject: GASTROENTEROLOGIA Year: 2009 Document type: Article Affiliation country: Canada Country of publication: United kingdom

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