Daunorubicin-loaded magnetic nanoparticles of Fe(3)O(4) greatly enhance the responses of multidrug-resistant K562 leukemic cells in a nude mouse xenograft model to chemotherapy.

Lai, Bin-Bin; Chen, Bao-An; Cheng, Jian; Gao, Feng; Xu, Wen-Lin; Ding, Jia-Hua; Gao, Chong; Sun, Xin-Chen; Li, Guo-Hong; Chen, Wen-Ji; Liu, Li-Jie; Li, Xiao-Mao; Wang, Xue-Mei

Daunorubicin-loaded magnetic nanoparticles of Fe(3)O(4) greatly enhance the responses of multidrug-resistant K562 leukemic cells in a nude mouse xenograft model to chemotherapy.

Lai, Bin-Bin; Chen, Bao-An; Cheng, Jian; Gao, Feng; Xu, Wen-Lin; Ding, Jia-Hua; Gao, Chong; Sun, Xin-Chen; Li, Guo-Hong; Chen, Wen-Ji; Liu, Li-Jie; Li, Xiao-Mao; Wang, Xue-Mei.

Affiliation

Lai BB; Department of Hematology, Zhongda Hospital, Clinical Medical College, Southeast University, Nanjing 210009, Jiangsu Province, China.

Zhongguo Shi Yan Xue Ye Xue Za Zhi ; 17(2): 345-51, 2009 Apr.

Article in En | MEDLINE | ID: mdl-19379564

Subject(s)

Daunorubicin/administration & dosage; Daunorubicin/therapeutic use; Leukemia/drug therapy; Animals; Daunorubicin/pharmacology; Drug Carriers; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; K562 Cells; Magnetics; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles/administration & dosage; Treatment Outcome; Xenograft Model Antitumor Assays

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / Daunorubicin Limits: Animals / Female / Humans Language: En Journal: Zhongguo Shi Yan Xue Ye Xue Za Zhi Journal subject: HEMATOLOGIA Year: 2009 Document type: Article Affiliation country: China Country of publication: China

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