Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.

Liu, Wen-bin; Liu, Jin-yi; Ao, Lin; Zhou, Zi-yuan; Zhou, Yan-hong; Cui, Zhi-hong; Yang, Huan; Cao, Jia

Liu, Wen-bin; Liu, Jin-yi; Ao, Lin; Zhou, Zi-yuan; Zhou, Yan-hong; Cui, Zhi-hong; Yang, Huan; Cao, Jia.

Affiliation

Liu WB; Department of Hygienic Toxicology, Preventive Medical College, Third Military Medical University, Key Laboratory of Medical Protection for Electromagnetic Radiation, Ministry of Education of China, Chongqing 400038, PR China. jinyiliutmmu@163.com

Toxicol Lett ; 189(1): 5-13, 2009 Aug 25.

Article in En | MEDLINE | ID: mdl-19409458

Subject(s)

Cocarcinogenesis; DNA Methylation/drug effects; Diethylnitrosamine/toxicity; Lung Neoplasms/chemically induced; Lung/drug effects; Methylcholanthrene/toxicity; Animals; Azacitidine/analogs & derivatives; Azacitidine/pharmacology; Cell Line; Cyclin-Dependent Kinase Inhibitor p15/genetics; Cyclin-Dependent Kinase Inhibitor p16/genetics; Decitabine; Female; Immunohistochemistry; Lung/metabolism; Lung/pathology; Lung Neoplasms/genetics; Lung Neoplasms/metabolism; Lung Neoplasms/pathology; Male; Microdissection; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cocarcinogenesis / DNA Methylation / Diethylnitrosamine / Lung / Lung Neoplasms / Methylcholanthrene Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Lett Year: 2009 Document type: Article Country of publication: Netherlands

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google