STAT3 transcription factor is constitutively activated and is oncogenic in nasal-type NK/T-cell lymphoma.

Coppo, P; Gouilleux-Gruart, V; Huang, Y; Bouhlal, H; Bouamar, H; Bouchet, S; Perrot, C; Vieillard, V; Dartigues, P; Gaulard, P; Agbalika, F; Douay, L; Lassoued, K; Gorin, N-C

Coppo, P; Gouilleux-Gruart, V; Huang, Y; Bouhlal, H; Bouamar, H; Bouchet, S; Perrot, C; Vieillard, V; Dartigues, P; Gaulard, P; Agbalika, F; Douay, L; Lassoued, K; Gorin, N-C.

Affiliation

Coppo P; Service d'Hématologie et de Thérapie Cellulaire, AP-HP, Hôpital Saint-Antoine, Paris, France. paulcoppo@aol.com

Leukemia ; 23(9): 1667-78, 2009 Sep.

Article in En | MEDLINE | ID: mdl-19421230

Subject(s)

Killer Cells, Natural/pathology; Lymphoma, T-Cell/etiology; Nose Neoplasms/etiology; STAT3 Transcription Factor/physiology; Animals; Extracellular Signal-Regulated MAP Kinases/physiology; Female; Humans; Interferon-gamma/biosynthesis; Janus Kinase 2/physiology; Lymphoma, T-Cell/genetics; Lymphoma, T-Cell/immunology; Lymphoma, T-Cell/pathology; Male; Mice; Mice, SCID; Middle Aged; Nose Neoplasms/genetics; Nose Neoplasms/immunology; Nose Neoplasms/pathology; Phosphorylation; STAT3 Transcription Factor/antagonists & inhibitors; bcl-X Protein/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Killer Cells, Natural / Nose Neoplasms / Lymphoma, T-Cell / STAT3 Transcription Factor Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2009 Document type: Article Affiliation country: France Country of publication: United kingdom

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