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Is the gamma interferon assay in cattle influenced by multiple tuberculin injections?
Rangen, Sheila A; Surujballi, Om P; Lutze-Wallace, Cyril; Lees, V Wayne.
Affiliation
  • Rangen SA; Lomsnes Veterinary Hospital, 3450-50 Avenue, Red Deer, Alberta T4N 3Y4, Canada. sar135@mail.usask.ca
Can Vet J ; 50(3): 270-4, 2009 Mar.
Article in En | MEDLINE | ID: mdl-19436478
ABSTRACT
Along with other developed countries, Canada is interested in adopting the gamma interferon (IFN-gamma) assay to test for bovine tuberculosis (TB). This study compared results of using the IFN-gamma assay in a large number of field-tested cattle in Manitoba, some previously tested with a caudal fold test (CFT) only, and others injected with tuberculins for both a CFT and a comparative cervical test (CCT). Parallel testing further compared the IFN-gamma assay and CCT results with the confirmed TB status of the animal (culture, histopathologic examination, polymerase chain reaction). Results from IFN-gamma assays did not differ following the CFT versus CFT and CCT injections. Parallel testing demonstrated an apparent higher prevalence of tuberculosis for the IFN-gamma assay versus CCT, which will assist in earlier removal of exposed animals and, ultimately, prevent populations from becoming infected.
Subject(s)

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculin / Tuberculosis, Bovine / Tuberculin Test / Interferon-gamma / Mycobacterium bovis Type of study: Diagnostic_studies / Risk_factors_studies Limits: Animals Country/Region as subject: America do norte Language: En Journal: Can Vet J Year: 2009 Document type: Article Affiliation country: Canada

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tuberculin / Tuberculosis, Bovine / Tuberculin Test / Interferon-gamma / Mycobacterium bovis Type of study: Diagnostic_studies / Risk_factors_studies Limits: Animals Country/Region as subject: America do norte Language: En Journal: Can Vet J Year: 2009 Document type: Article Affiliation country: Canada