Melanin-concentrating hormone and immune function.
Peptides
; 30(11): 2076-80, 2009 Nov.
Article
in En
| MEDLINE
| ID: mdl-19450627
ABSTRACT
To date, melanin-concentrating hormone (MCH) has been generally considered as peptide acting almost exclusively in the central nervous system. In the present paper, we revise the experimental evidence, demonstrating that MCH and its receptors are expressed by cells of the immune system and directly influence the response of these cells in some circumstances. This therefore supports the idea that, as with other peptides, MCH could be considered as a modulator of the immune system. Moreover, we suggest that this could have important implications in several immune-mediated disorders and affirm that there is a clear need for further investigation.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pituitary Hormones
/
Hypothalamic Hormones
/
Immune System
/
Melanins
Limits:
Animals
/
Humans
Language:
En
Journal:
Peptides
Year:
2009
Document type:
Article
Affiliation country:
Belgium