[Therapeutic effect of para-toluenesulfonamide on transplanted hepatocarcinoma in nude mice].
Nan Fang Yi Ke Da Xue Xue Bao
; 29(5): 1024-5, 2009 May.
Article
in Zh
| MEDLINE
| ID: mdl-19460736
ABSTRACT
OBJECTIVE:
To study the effect of of percutaneous para-toluenesulfonamide (PTS) injection on transplanted hepatocarcinoma in nude mice.METHODS:
Sixty nude mice with subcutaneous transplanted hepatocarcinoma were randomized into 6 groups, namely PTS, chemotherapy, radiotherapy, PTS+chemotherapy, PTS+radiotherapy and control groups. PTS were injected into the tumor in the nude mouse models as indicated, and the tumor growth rate and survival time of the mice were recorded.RESULTS:
All the treatments resulted in effective arrest of the tumor growth, but the effects of PTS+chemotherapy and PTS+radiotherapy were more obvious. No significant difference in the survival time of the mice were noted between the groups.CONCLUSION:
PTS+chemotherapy and PTS+radiotherapy are safe and reliable, and produces better effects than either radiotherapy or chemotherapy alone.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Radiotherapy
/
Sulfonamides
/
Toluene
/
Antineoplastic Combined Chemotherapy Protocols
/
Liver Neoplasms, Experimental
Limits:
Animals
Language:
Zh
Journal:
Nan Fang Yi Ke Da Xue Xue Bao
Year:
2009
Document type:
Article
Affiliation country:
China