Electrochemistry of cytochromes p450: analysis of current-voltage characteristics of electrodes with immobilized cytochromes p450 for the screening of substrates and inhibitors.

Shumyantseva, V V; Bulko, T V; Kuznetsova, G P; Samenkova, N F; Archakov, A I

Shumyantseva, V V; Bulko, T V; Kuznetsova, G P; Samenkova, N F; Archakov, A I.

Affiliation

Shumyantseva VV; Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, 119121, Russia. viktoria.shumyantseva@ibmc.msk.ru

Biochemistry (Mosc) ; 74(4): 438-44, 2009 Apr.

Article in En | MEDLINE | ID: mdl-19463098

Subject(s)

Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System/chemistry; Drug Evaluation, Preclinical/methods; Electrochemistry/methods; Enzyme Inhibitors/chemistry; Enzymes, Immobilized/antagonists & inhibitors; Enzymes, Immobilized/chemistry; Animals; Cytochrome P-450 Enzyme System/metabolism; Electrodes; Enzymes, Immobilized/metabolism; Mycobacterium tuberculosis/chemistry; Mycobacterium tuberculosis/enzymology; Rabbits; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 Enzyme System / Drug Evaluation, Preclinical / Electrochemistry / Enzyme Inhibitors / Enzymes, Immobilized / Cytochrome P-450 Enzyme Inhibitors Type of study: Diagnostic_studies / Evaluation_studies / Screening_studies Limits: Animals Language: En Journal: Biochemistry (Mosc) Year: 2009 Document type: Article Affiliation country: RUSSIA Country of publication: United States

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