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RSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.
Larrea, Michelle D; Hong, Feng; Wander, Seth A; da Silva, Thiago G; Helfman, David; Lannigan, Deborah; Smith, Jeffrey A; Slingerland, Joyce M.
Affiliation
  • Larrea MD; Department of Biochemistry and Molecular Biology, Braman Family Breast Cancer Institute, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL 33136, USA.
Proc Natl Acad Sci U S A ; 106(23): 9268-73, 2009 Jun 09.
Article in En | MEDLINE | ID: mdl-19470470
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Movement / RhoA GTP-Binding Protein / Ribosomal Protein S6 Kinases, 90-kDa / Intracellular Signaling Peptides and Proteins Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cell Movement / RhoA GTP-Binding Protein / Ribosomal Protein S6 Kinases, 90-kDa / Intracellular Signaling Peptides and Proteins Limits: Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States