Sonic hedgehog: its expression in a healing cornea and its role in neovascularization.

Fujita, Kyoko; Miyamoto, Takeshi; Saika, Shizuya

Fujita, Kyoko; Miyamoto, Takeshi; Saika, Shizuya.

Affiliation

Fujita K; Department of Ophthalmology, Wakayama Medical University, Kimiidera, Wakayama, Japan. kyoko@wakayama-med.ac.jp

Mol Vis ; 15: 1036-44, 2009 May 18.

Article in En | MEDLINE | ID: mdl-19471603

Subject(s)

Corneal Injuries; Hedgehog Proteins/pharmacology; Hedgehog Proteins/physiology; Neovascularization, Physiologic; Wound Healing; Alkalies/adverse effects; Animals; Cell Line; Chemokine CCL2/metabolism; Cornea/blood supply; Cornea/ultrastructure; Corneal Diseases/chemically induced; Gene Expression/drug effects; Hedgehog Proteins/antagonists & inhibitors; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Neovascularization, Physiologic/drug effects; Platelet Endothelial Cell Adhesion Molecule-1/metabolism; Signal Transduction/drug effects; Transforming Growth Factor beta1/metabolism; Umbilical Veins/cytology; Vascular Endothelial Growth Factor A/metabolism; Veratrum Alkaloids/metabolism; Wound Healing/drug effects; Wound Healing/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Wound Healing / Neovascularization, Physiologic / Hedgehog Proteins / Corneal Injuries Limits: Animals / Humans Language: En Journal: Mol Vis Journal subject: BIOLOGIA MOLECULAR / OFTALMOLOGIA Year: 2009 Document type: Article Affiliation country: Japan

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