Addressing the challenges of the clinical application of pharmacogenetic testing.
Clin Pharmacol Ther
; 86(1): 28-31, 2009 Jul.
Article
in En
| MEDLINE
| ID: mdl-19536122
ABSTRACT
Pharmacogenomics aims to use molecular genetic markers to predict treatment outcome. Indeed, within the past decade there has been a rapid emergence of pharmacogenetic tests to aid clinicians in predicting efficacy or toxicity for some drugs. Despite this major advance in therapeutic drug management, there remain challenges to the appropriate use of pharmacogenetic tests. We discuss UGT1A1 pharmacogenetic testing to illustrate the knowledge gaps impeding widespread use of pharmacogenetic tests in the clinical setting.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pharmacogenetics
/
Genetic Testing
Type of study:
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Clin Pharmacol Ther
Year:
2009
Document type:
Article
Affiliation country:
United States