Cilostazol reduces proliferation through c-Myc down-regulation in MDCK cells.

Muñoz, Balam; Huerta, Miriam; López-Bayghen, Esther

Muñoz, Balam; Huerta, Miriam; López-Bayghen, Esther.

Affiliation

Muñoz B; Departamento de Genética y Biología Molecular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México, DF 07000, México.

Eur J Pharmacol ; 616(1-3): 22-30, 2009 Aug 15.

Article in En | MEDLINE | ID: mdl-19545562

Subject(s)

Down-Regulation/drug effects; Proto-Oncogene Proteins c-myc/genetics; Tetrazoles/pharmacology; Animals; Apoptosis/drug effects; Base Sequence; Cell Cycle/drug effects; Cell Line; Cell Proliferation/drug effects; Cilostazol; Cyclic AMP/metabolism; Cyclic AMP-Dependent Protein Kinases/metabolism; DNA/metabolism; Disease Progression; Dogs; Extracellular Signal-Regulated MAP Kinases/metabolism; Humans; Phosphodiesterase Inhibitors/pharmacology; Phosphodiesterase Inhibitors/therapeutic use; Polycystic Kidney Diseases/drug therapy; Polycystic Kidney Diseases/metabolism; Proto-Oncogene Proteins c-myc/metabolism; Tetrazoles/therapeutic use; Transcription Factors/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tetrazoles / Down-Regulation / Proto-Oncogene Proteins c-myc Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Eur J Pharmacol Year: 2009 Document type: Article Country of publication: Netherlands

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