ADAM23 negatively modulates alpha(v)beta(3) integrin activation during metastasis.

Verbisck, Newton V; Costa, Erico T; Costa, Fabrício F; Cavalher, Felícia P; Costa, Michele D M; Muras, Angelita; Paixão, Valéria A; Moura, Ricardo; Granato, Mariana F; Ierardi, Daniela F; Machado, Tamara; Melo, Fabiana; Ribeiro, Karina B; Cunha, Isabela W; Lima, Vladmir C C; Maciel, Maria do Socorro; Carvalho, André L; Soares, Fernando F; Zanata, Silvio; Sogayar, Mari C; Chammas, Roger; Camargo, Anamaria A

Verbisck, Newton V; Costa, Erico T; Costa, Fabrício F; Cavalher, Felícia P; Costa, Michele D M; Muras, Angelita; Paixão, Valéria A; Moura, Ricardo; Granato, Mariana F; Ierardi, Daniela F; Machado, Tamara; Melo, Fabiana; Ribeiro, Karina B; Cunha, Isabela W; Lima, Vladmir C C; Maciel, Maria do Socorro; Carvalho, André L; Soares, Fernando F; Zanata, Silvio; Sogayar, Mari C; Chammas, Roger; Camargo, Anamaria A.

Affiliation

Verbisck NV; Laboratory of Molecular Biology and Genomics, Ludwig Institute for Cancer Research, São Paulo SP, Brazil.

Cancer Res ; 69(13): 5546-52, 2009 Jul 01.

Article in En | MEDLINE | ID: mdl-19549921

Subject(s)

ADAM Proteins/genetics; Integrin alphaVbeta3/genetics; Neoplasm Metastasis/genetics; ADAM Proteins/deficiency; ADAM Proteins/physiology; Animals; Cell Adhesion/genetics; Cell Line, Tumor; Cell Movement; DNA Methylation; DNA, Neoplasm/genetics; Female; Humans; Integrin alphaVbeta3/physiology; Lung Neoplasms/genetics; Lung Neoplasms/pathology; Mice; Mice, SCID; Neoplasm Metastasis/pathology; Polymerase Chain Reaction; RNA, Catalytic/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Integrin alphaVbeta3 / ADAM Proteins / Neoplasm Metastasis Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2009 Document type: Article Affiliation country: Brazil Country of publication: United States

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