Investigation and prediction of the severity of p53 mutants using parameters from structural calculations.

Carlsson, Jonas; Soussi, Thierry; Persson, Bengt

Carlsson, Jonas; Soussi, Thierry; Persson, Bengt.

Affiliation

Carlsson J; IFM Bioinformatics, Linköping University, Sweden. jonca@ifm.liu.se

FEBS J ; 276(15): 4142-55, 2009 Aug.

Article in En | MEDLINE | ID: mdl-19558493

Subject(s)

Breast Neoplasms/genetics; Mutation; Tumor Suppressor Protein p53/genetics; Algorithms; Cyclin-Dependent Kinase Inhibitor p21/genetics; Cyclin-Dependent Kinase Inhibitor p21/metabolism; Female; Humans; Models, Molecular; Neoplasms/genetics; Neoplasms/prevention & control; Promoter Regions, Genetic; Protein Binding; Protein Conformation; Severity of Illness Index; Tumor Suppressor Protein p53/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Tumor Suppressor Protein p53 / Mutation Type of study: Prognostic_studies / Risk_factors_studies Limits: Female / Humans Language: En Journal: FEBS J Journal subject: BIOQUIMICA Year: 2009 Document type: Article Affiliation country: Sweden Country of publication: United kingdom

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