Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia.

Halene, T B; Ehrlichman, R S; Liang, Y; Christian, E P; Jonak, G J; Gur, T L; Blendy, J A; Dow, H C; Brodkin, E S; Schneider, F; Gur, R C; Siegel, S J

Halene, T B; Ehrlichman, R S; Liang, Y; Christian, E P; Jonak, G J; Gur, T L; Blendy, J A; Dow, H C; Brodkin, E S; Schneider, F; Gur, R C; Siegel, S J.

Affiliation

Halene TB; Department of Psychiatry, University of Pennsylvania, Philadelphia, PA 19104, USA.

Genes Brain Behav ; 8(7): 661-75, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19563516

Subject(s)

Brain Chemistry/genetics; Brain/metabolism; Genetic Predisposition to Disease/genetics; Receptors, N-Methyl-D-Aspartate/genetics; Schizophrenia/genetics; Schizophrenia/metabolism; Animals; Anxiety/genetics; Auditory Diseases, Central/genetics; Auditory Diseases, Central/metabolism; Auditory Diseases, Central/physiopathology; Behavior, Animal/physiology; Brain/physiopathology; Disease Models, Animal; Evoked Potentials/genetics; Female; Genotype; Glutamic Acid/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neural Inhibition/genetics; Perceptual Disorders/genetics; Perceptual Disorders/metabolism; Perceptual Disorders/physiopathology; Phenotype; Schizophrenia/physiopathology; Social Behavior; Visual Pathways/metabolism; Visual Pathways/physiopathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizophrenia / Brain / Brain Chemistry / Receptors, N-Methyl-D-Aspartate / Genetic Predisposition to Disease Limits: Animals Language: En Journal: Genes Brain Behav Journal subject: CIENCIAS DO COMPORTAMENTO / GENETICA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United kingdom

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