Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.21.

An, Qian; Wright, Sarah L; Moorman, Anthony V; Parker, Helen; Griffiths, Mike; Ross, Fiona M; Davies, Teresa; Harrison, Christine J; Strefford, Jon C

An, Qian; Wright, Sarah L; Moorman, Anthony V; Parker, Helen; Griffiths, Mike; Ross, Fiona M; Davies, Teresa; Harrison, Christine J; Strefford, Jon C.

Affiliation

An Q; Cancer Sciences Division, University of Southampton, Southampton, UK.

Haematologica ; 94(8): 1164-9, 2009 Aug.

Article in En | MEDLINE | ID: mdl-19586940

Subject(s)

Chromosomes, Human, Pair 20/genetics; Chromosomes, Human, Pair 9/genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/genetics; Translocation, Genetic; Adolescent; Base Sequence; Centromere/genetics; Child; Child, Preschool; Chromosome Breakage; Chromosome Mapping; Cohort Studies; Female; Genetic Heterogeneity; Humans; In Situ Hybridization, Fluorescence; Infant; Male; Microfilament Proteins; Molecular Sequence Data; Nuclear Proteins/genetics; PAX5 Transcription Factor/genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology; RNA-Binding Proteins; Recurrence; Repressor Proteins/genetics; Sequence Homology, Nucleic Acid; Transcription Factors/genetics; Young Adult

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Translocation, Genetic / Chromosomes, Human, Pair 9 / Chromosomes, Human, Pair 20 / Precursor Cell Lymphoblastic Leukemia-Lymphoma Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant / Male Language: En Journal: Haematologica Year: 2009 Document type: Article Country of publication: Italy

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