Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells.

Jürgens, Birgit; Hainz, Ursula; Fuchs, Dietmar; Felzmann, Thomas; Heitger, Andreas

Jürgens, Birgit; Hainz, Ursula; Fuchs, Dietmar; Felzmann, Thomas; Heitger, Andreas.

Affiliation

Jürgens B; Children's Cancer Research Institute, St Anna Children's Hospital, Vienna, Austria.

Blood ; 114(15): 3235-43, 2009 Oct 08.

Article in En | MEDLINE | ID: mdl-19625705

Subject(s)

Dendritic Cells/immunology; Indoleamine-Pyrrole 2,3,-Dioxygenase/immunology; Interferon-gamma/immunology; Monocytes/immunology; T-Lymphocytes, Regulatory/immunology; Cell Differentiation/drug effects; Cell Differentiation/immunology; Cells, Cultured; Coculture Techniques; Dendritic Cells/cytology; Dendritic Cells/enzymology; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase/antagonists & inhibitors; Indoleamine-Pyrrole 2,3,-Dioxygenase/metabolism; Indoles/pharmacology; Inflammation Mediators/immunology; Interferon-gamma/metabolism; Interferon-gamma/pharmacology; Lipopolysaccharides/pharmacology; Monocytes/cytology; Monocytes/enzymology; T-Lymphocytes, Regulatory/cytology; T-Lymphocytes, Regulatory/enzymology; Thiohydantoins/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Monocytes / Interferon-gamma / T-Lymphocytes, Regulatory / Indoleamine-Pyrrole 2,3,-Dioxygenase Limits: Humans Language: En Journal: Blood Year: 2009 Document type: Article Affiliation country: Austria Country of publication: United States

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