Genetic Predisposition to Disease/genetics; Mutation/genetics; Nervous System Malformations/genetics; Ocular Motility Disorders/genetics; Receptors, Immunologic/genetics; Scoliosis/genetics; Adolescent; Adult; Allelic Imbalance/genetics; Brain Stem/abnormalities; Brain Stem/physiopathology; Cerebellum/abnormalities; Cerebellum/physiopathology; Child; Chromosome Mapping; DNA Mutational Analysis; Disease Progression; Female; Genetic Markers/genetics; Genetic Testing; Genetic Variation/genetics; Humans; Magnetic Resonance Imaging; Male; Nervous System Malformations/metabolism; Nervous System Malformations/pathology; Ocular Motility Disorders/complications; Ocular Motility Disorders/physiopathology; Receptors, Cell Surface; Receptors, Immunologic/metabolism; Scoliosis/complications; Scoliosis/physiopathology; Tunisia/ethnology; Young Adult