Interactions of gallic acid, resveratrol, quercetin and aspirin at the platelet cyclooxygenase-1 level. Functional and modelling studies.

Crescente, Marilena; Jessen, Gisela; Momi, Stefania; Höltje, Hans-Dieter; Gresele, Paolo; Cerletti, Chiara; de Gaetano, Giovanni

Crescente, Marilena; Jessen, Gisela; Momi, Stefania; Höltje, Hans-Dieter; Gresele, Paolo; Cerletti, Chiara; de Gaetano, Giovanni.

Affiliation

Crescente M; Catholic University, Largo Gemelli 1, 86100 Campobasso, Italy.

Thromb Haemost ; 102(2): 336-46, 2009 Aug.

Article in En | MEDLINE | ID: mdl-19652885

Subject(s)

Aspirin/administration & dosage; Blood Platelets/drug effects; Blood Platelets/enzymology; Cyclooxygenase 1/blood; Gallic Acid/administration & dosage; Quercetin/administration & dosage; Stilbenes/administration & dosage; Animals; Antioxidants/administration & dosage; Arachidonic Acid/administration & dosage; Cyclooxygenase 1/chemistry; Drug Interactions; Humans; In Vitro Techniques; Male; Membrane Proteins/blood; Membrane Proteins/chemistry; Mice; Models, Biological; Models, Molecular; Platelet Aggregation/drug effects; Platelet Aggregation Inhibitors/administration & dosage; Reactive Oxygen Species/blood; Resveratrol; Thermodynamics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quercetin / Stilbenes / Blood Platelets / Aspirin / Cyclooxygenase 1 / Gallic Acid Limits: Animals / Humans / Male Language: En Journal: Thromb Haemost Year: 2009 Document type: Article Affiliation country: Italy

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