Mechanism of UVB-induced wrinkling of the skin: paracrine cytokine linkage between keratinocytes and fibroblasts leading to the stimulation of elastase.

Imokawa, Genji

Imokawa, Genji.

Affiliation

Imokawa G; School of Bioscience and Biotechnology, Tokyo University of Technology, Tokyo, Japan. imokawa@bs.teu.ac.jp

J Investig Dermatol Symp Proc ; 14(1): 36-43, 2009 Aug.

Article in En | MEDLINE | ID: mdl-19675551

Subject(s)

Skin Aging/radiation effects; Ultraviolet Rays/adverse effects; Animals; Cytokines/metabolism; Elastic Tissue/physiology; Elastic Tissue/radiation effects; Elasticity/drug effects; Elasticity/physiology; Elasticity/radiation effects; Enzyme Inhibitors/pharmacology; Fibroblasts/pathology; Fibroblasts/physiology; Fibroblasts/radiation effects; Humans; Keratinocytes/pathology; Keratinocytes/physiology; Keratinocytes/radiation effects; Microscopy, Electron, Scanning; Pancreatic Elastase/antagonists & inhibitors; Pancreatic Elastase/metabolism; Paracrine Communication/radiation effects; Skin Aging/drug effects; Skin Aging/pathology; Skin Aging/physiology; Up-Regulation/radiation effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ultraviolet Rays / Skin Aging Limits: Animals / Humans Language: En Journal: J Investig Dermatol Symp Proc Journal subject: DERMATOLOGIA Year: 2009 Document type: Article Affiliation country: Japan Country of publication: United States

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