Evidence that opioids may have toll-like receptor 4 and MD-2 effects.

Hutchinson, Mark R; Zhang, Yingning; Shridhar, Mitesh; Evans, John H; Buchanan, Madison M; Zhao, Tina X; Slivka, Peter F; Coats, Benjamen D; Rezvani, Niloofar; Wieseler, Julie; Hughes, Travis S; Landgraf, Kyle E; Chan, Stefanie; Fong, Stephanie; Phipps, Simon; Falke, Joseph J; Leinwand, Leslie A; Maier, Steven F; Yin, Hang; Rice, Kenner C; Watkins, Linda R

Hutchinson, Mark R; Zhang, Yingning; Shridhar, Mitesh; Evans, John H; Buchanan, Madison M; Zhao, Tina X; Slivka, Peter F; Coats, Benjamen D; Rezvani, Niloofar; Wieseler, Julie; Hughes, Travis S; Landgraf, Kyle E; Chan, Stefanie; Fong, Stephanie; Phipps, Simon; Falke, Joseph J; Leinwand, Leslie A; Maier, Steven F; Yin, Hang; Rice, Kenner C; Watkins, Linda R.

Affiliation

Hutchinson MR; Department of Psychology and The Center for Neuroscience, University of Colorado at Boulder, Boulder, CO 80309-0345, USA

Brain Behav Immun ; 24(1): 83-95, 2010 Jan.

Article in En | MEDLINE | ID: mdl-19679181

Subject(s)

Analgesics, Opioid/pharmacology; Lymphocyte Antigen 96/drug effects; Toll-Like Receptor 4/drug effects; Analgesia; Animals; Cell Line; Computer Simulation; Hot Temperature; Hyperalgesia/psychology; Infusion Pumps; Injections, Spinal; Lymphocyte Antigen 96/agonists; Lymphocyte Antigen 96/antagonists & inhibitors; Macrophages/drug effects; Male; Mice; Naloxone/pharmacology; Narcotic Antagonists/pharmacology; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time/drug effects; Receptors, Opioid, mu/agonists; Receptors, Opioid, mu/antagonists & inhibitors; Receptors, Opioid, mu/drug effects; Signal Transduction/drug effects; Substance Withdrawal Syndrome/psychology; Toll-Like Receptor 4/agonists; Toll-Like Receptor 4/antagonists & inhibitors; Transfection

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lymphocyte Antigen 96 / Toll-Like Receptor 4 / Analgesics, Opioid Type of study: Prognostic_studies Limits: Animals Language: En Journal: Brain Behav Immun Journal subject: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Year: 2010 Document type: Article Affiliation country: United States Country of publication: Netherlands

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