Activity of telomerase in ovarian cancer cells. Clinical implications.

Lubin, J; Markowska, J; Markowska, A; Stanislawiak, J; Lukaszewski, T

Lubin, J; Markowska, J; Markowska, A; Stanislawiak, J; Lukaszewski, T.

Affiliation

Lubin J; Department of Gynaecological Oncology, Poznan University of Medical Sciences, Poznan, Poland. jolaostap@wp.pl

Clin Exp Obstet Gynecol ; 36(2): 91-6, 2009.

Article in En | MEDLINE | ID: mdl-19688950

ABSTRACT

Estimation of telomerase activity in cell nuclei of ovarian malignant tumours may provide an independent prognostic index. The test for telomerase activity in tumour cell nuclei may be accepted as a useful diagnostic test with application for differential diagnoses of benign ovarian tumours vs tumours of a borderline or malignant character.

Subject(s)

Adenocarcinoma/enzymology; Cell Nucleus/enzymology; Ovarian Neoplasms/enzymology; Telomerase/metabolism; Adult; Aged; CA-125 Antigen/analysis; Case-Control Studies; Female; Humans; In Situ Hybridization, Fluorescence; Middle Aged; Neoplasm Staging; Ovarian Cysts/enzymology; Predictive Value of Tests; Survival Analysis; Ubiquitin-Protein Ligases/analysis

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Adenocarcinoma / Cell Nucleus / Telomerase Type of study: Observational_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Clin Exp Obstet Gynecol Year: 2009 Document type: Article Affiliation country: Poland Country of publication: Singapore

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