Antimetastatic, antineoplastic, and toxic effects of 4-hydroxycoumarin in a preclinical mouse melanoma model.

Salinas-Jazmín, Nohemí; de la Fuente, Marisol; Jaimez, Ruth; Pérez-Tapia, Mayra; Pérez-Torres, Armando; Velasco-Velázquez, Marco A

Salinas-Jazmín, Nohemí; de la Fuente, Marisol; Jaimez, Ruth; Pérez-Tapia, Mayra; Pérez-Torres, Armando; Velasco-Velázquez, Marco A.

Affiliation

Salinas-Jazmín N; Departamento de Farmacología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, Apdo. Postal 70-297, México, DF 04510, México.

Cancer Chemother Pharmacol ; 65(5): 931-40, 2010 Apr.

Article in En | MEDLINE | ID: mdl-19690859

Subject(s)

4-Hydroxycoumarins/therapeutic use; Antineoplastic Agents/therapeutic use; Melanoma, Experimental/drug therapy; 4-Hydroxycoumarins/adverse effects; Animals; Anticoagulants/adverse effects; Anticoagulants/therapeutic use; Antineoplastic Agents/adverse effects; Disease Models, Animal; Drug Evaluation, Preclinical; Kidney/drug effects; Kidney/pathology; Kidney/ultrastructure; Liver/drug effects; Liver/pathology; Lung/drug effects; Lung/pathology; Lung/ultrastructure; Male; Melanoma, Experimental/pathology; Melanoma, Experimental/ultrastructure; Mice; Mice, Inbred C57BL; Neoplasm Metastasis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Melanoma, Experimental / 4-Hydroxycoumarins / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cancer Chemother Pharmacol Year: 2010 Document type: Article Country of publication: Germany

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