[Immunoglobulin treatment for neonatal hemochromatosis: a case report in a context of immunoglobulin delivery quotas]. / Traitement par immunoglobuline polyvalente en situation de contingentement. A propos d'un cas à risque d'hémochromatose néonatale.
Ann Pharm Fr
; 67(5): 304-9, 2009 Sep.
Article
in Fr
| MEDLINE
| ID: mdl-19695366
ABSTRACT
Neonatal hemochromatosis is a rare disease characterized by iron deposits in several organs. The natural course leads to lethal liver failure. A preventive treatment was recently introduced high-dose intravenous immunoglobulins during pregnancy to prevent fetomaternal allo-immunization. Nevertheless, the prescription of massive quantities of immunoglobulins can lead to a drug shortage which the hospital pharmacist must deal with. We report the case of a pregnant woman with high risk of transmitting neonatal hemochromatosis. We discuss the pharmaceutical difficulties encountered when managing patients with a high risk of neonatal hemochromatosis in the context of immunoglobulin shortage with the delivery quotas established by the French National Health Authority. In this context, a national stock would be useful to deal with rare diseases and thus to support hospitals.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Immunoglobulins
/
Hemochromatosis
Limits:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Language:
Fr
Journal:
Ann Pharm Fr
Year:
2009
Document type:
Article
Affiliation country:
France