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Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonists.
Lange, Jos H M; den Hartog, Arnold P; van der Neut, Martina A W; van Vliet, Bernard J; Kruse, Chris G.
Affiliation
  • Lange JH; Solvay Pharmaceuticals, Chemical Design and Synthesis Unit, Research Laboratories, C. J. van Houtenlaan 36, 1381 CP Weesp, The Netherlands. jos.lange@solvay.com
Bioorg Med Chem Lett ; 19(19): 5675-8, 2009 Oct 01.
Article in En | MEDLINE | ID: mdl-19699640
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridazines / Receptor, Cannabinoid, CB1 Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Document type: Article Affiliation country: Netherlands
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridazines / Receptor, Cannabinoid, CB1 Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Document type: Article Affiliation country: Netherlands