High-throughput HPLC-MS/MS method to determine ibandronate in human plasma for pharmacokinetic applications.

Tarcomnicu, Isabela; Gheorghe, Mihaela Cristina; Silvestro, Luigi; Savu, Simona Rizea; Boaru, Irina; Tudoroniu, Ariana

Tarcomnicu, Isabela; Gheorghe, Mihaela Cristina; Silvestro, Luigi; Savu, Simona Rizea; Boaru, Irina; Tudoroniu, Ariana.

Affiliation

Tarcomnicu I; Pharma Serv Int'l SRL, 52 Sabinelor Str., 5th District, 050853 Bucharest, Romania.

J Chromatogr B Analyt Technol Biomed Life Sci ; 877(27): 3159-68, 2009 Oct 01.

Article in En | MEDLINE | ID: mdl-19700377

Subject(s)

Chromatography, High Pressure Liquid/methods; Diphosphonates/blood; Tandem Mass Spectrometry/methods; Bone Density Conservation Agents/blood; Bone Density Conservation Agents/pharmacokinetics; Diphosphonates/pharmacokinetics; Drug Stability; Humans; Ibandronic Acid; Linear Models; Reproducibility of Results; Sensitivity and Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatography, High Pressure Liquid / Diphosphonates / Tandem Mass Spectrometry Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2009 Document type: Article Affiliation country: Romania Country of publication: Netherlands

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