Genome-wide location analysis reveals a role for Sub1 in RNA polymerase III transcription.
Proc Natl Acad Sci U S A
; 106(34): 14265-70, 2009 Aug 25.
Article
in En
| MEDLINE
| ID: mdl-19706510
ABSTRACT
Human PC4 and the yeast ortholog Sub1 have multiple functions in RNA polymerase II transcription. Genome-wide mapping revealed that Sub1 is present on Pol III-transcribed genes. Sub1 was found to interact with components of the Pol III transcription system and to stimulate the initiation and reinitiation steps in a system reconstituted with all recombinant factors. Sub1 was required for optimal Pol III gene transcription in exponentially growing cells.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Transcription Factors
/
Transcription, Genetic
/
RNA Polymerase III
/
Saccharomyces cerevisiae Proteins
/
DNA-Binding Proteins
Language:
En
Journal:
Proc Natl Acad Sci U S A
Year:
2009
Document type:
Article
Affiliation country:
France
Country of publication:
EEUU
/
ESTADOS UNIDOS
/
ESTADOS UNIDOS DA AMERICA
/
EUA
/
UNITED STATES
/
UNITED STATES OF AMERICA
/
US
/
USA