In-depth evaluation of the cycloaddition--retro-Diels--Alder reaction for in vivo targeting with [(111)In]-DTPA-RGD conjugates.

Laverman, Peter; Meeuwissen, Silvie A; van Berkel, Sander S; Oyen, Wim J G; van Delft, Floris L; Rutjes, Floris P J T; Boerman, Otto C

Laverman, Peter; Meeuwissen, Silvie A; van Berkel, Sander S; Oyen, Wim J G; van Delft, Floris L; Rutjes, Floris P J T; Boerman, Otto C.

Affiliation

Laverman P; Department of Nuclear Medicine, Radboud University Nijmegen Medical Centre, 6500 HB Nijmegen, The Netherlands. p.laverman@nucmed.umcn.nl

Nucl Med Biol ; 36(7): 749-57, 2009 Oct.

Article in En | MEDLINE | ID: mdl-19720287

Subject(s)

Indium Radioisotopes/chemistry; Oligopeptides/chemistry; Oligopeptides/metabolism; Pentetic Acid/chemistry; Animals; Biocompatible Materials/chemistry; Biocompatible Materials/metabolism; Biocompatible Materials/pharmacokinetics; Cell Line, Tumor; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Integrin alphaVbeta3/metabolism; Isotope Labeling; Kinetics; Male; Mice; Octanols/chemistry; Oligopeptides/pharmacokinetics; Temperature; Tissue Distribution; Water/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Indium Radioisotopes / Pentetic Acid Limits: Animals / Humans / Male Language: En Journal: Nucl Med Biol Journal subject: BIOLOGIA / MEDICINA NUCLEAR Year: 2009 Document type: Article Affiliation country: Netherlands Country of publication: United States

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