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Antibodies induced by dengue virus type 1 and 2 envelope domain III recombinant proteins in monkeys neutralize strains with different genotypes.
Bernardo, Lidice; Fleitas, Osmel; Pavón, Alequis; Hermida, Lisset; Guillén, Gerardo; Guzman, Maria G.
Affiliation
  • Bernardo L; Department of Virology, PAHO/WHO Collaborating Center for the Study of Dengue and Its Vector, Pedro Kourí Tropical Medicine Institute, Autopista Novia del Mediodía, km 6 1/2, P.O. Box 601, Marianao 13, Havana, Cuba.
Clin Vaccine Immunol ; 16(12): 1829-31, 2009 Dec.
Article in En | MEDLINE | ID: mdl-19726617
ABSTRACT
In the present work, we evaluated the neutralizing capacity of the antibodies induced by dengue virus type 1 and 2 envelope domain III recombinant proteins in monkeys against strains of different dengue virus type 1 and 2 genotypes. Here we demonstrated that dengue virus type 1 and 2 recombinant proteins induced high titers of neutralizing antibodies against different genotype strains.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Viral Envelope Proteins / Dengue / Dengue Virus / Dengue Vaccines / Antibodies, Viral Limits: Animals Language: En Journal: Clin Vaccine Immunol Journal subject: ALERGIA E IMUNOLOGIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2009 Document type: Article Affiliation country: Cuba
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Recombinant Proteins / Viral Envelope Proteins / Dengue / Dengue Virus / Dengue Vaccines / Antibodies, Viral Limits: Animals Language: En Journal: Clin Vaccine Immunol Journal subject: ALERGIA E IMUNOLOGIA / TECNICAS E PROCEDIMENTOS DE LABORATORIO Year: 2009 Document type: Article Affiliation country: Cuba