Role for the Burkholderia pseudomallei capsular polysaccharide encoded by the wcb operon in acute disseminated melioidosis.

Warawa, Jonathan M; Long, Dan; Rosenke, Rebecca; Gardner, Don; Gherardini, Frank C

Warawa, Jonathan M; Long, Dan; Rosenke, Rebecca; Gardner, Don; Gherardini, Frank C.

Affiliation

Warawa JM; Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana 59840.

Infect Immun ; 77(12): 5252-61, 2009 Dec.

Article in En | MEDLINE | ID: mdl-19752033

Subject(s)

Bacterial Capsules/immunology; Bacterial Capsules/physiology; Burkholderia pseudomallei/immunology; Burkholderia pseudomallei/pathogenicity; Melioidosis/microbiology; Virulence Factors/immunology; Virulence Factors/physiology; Animals; Bacterial Capsules/genetics; Burkholderia pseudomallei/genetics; Cell Line; Colony Count, Microbial; Cytokines/metabolism; Female; Gene Deletion; Liver/microbiology; Liver/pathology; Lung/microbiology; Lung/pathology; Macrophages/microbiology; Mice; Mice, Inbred BALB C; Operon; Severity of Illness Index; Spleen/microbiology; Spleen/pathology; Survival Analysis; Virulence Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Burkholderia pseudomallei / Bacterial Capsules / Virulence Factors / Melioidosis Type of study: Prognostic_studies Limits: Animals Language: En Journal: Infect Immun Year: 2009 Document type: Article Country of publication: United States

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