Estimating dormant and active hematopoietic stem cell kinetics through extensive modeling of bromodeoxyuridine label-retaining cell dynamics.

van der Wath, Richard C; Wilson, Anne; Laurenti, Elisa; Trumpp, Andreas; Liò, Pietro

van der Wath, Richard C; Wilson, Anne; Laurenti, Elisa; Trumpp, Andreas; Liò, Pietro.

Affiliation

van der Wath RC; Computer Laboratory, University of Cambridge, Cambridge, United Kingdom. rvanderwath@gmail.com

PLoS One ; 4(9): e6972, 2009 Sep 22.

Article in En | MEDLINE | ID: mdl-19771180

Subject(s)

Bromodeoxyuridine/pharmacology; Hematopoietic Stem Cells/cytology; Algorithms; Animals; Antimetabolites/pharmacology; Cell Cycle; Cell Proliferation; Computational Biology/methods; Hematopoietic Stem Cells/drug effects; Kinetics; Mice; Models, Biological; Models, Theoretical; Software; Stochastic Processes; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bromodeoxyuridine / Hematopoietic Stem Cells Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2009 Document type: Article Affiliation country: United kingdom Country of publication: United States

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