Manipulation of electrostatic and saccharide linker interactions in the design of efficient glycopolypeptide-based cholera toxin inhibitors.

Maheshwari, Ronak; Levenson, Eric A; Kiick, Kristi L

Maheshwari, Ronak; Levenson, Eric A; Kiick, Kristi L.

Affiliation

Maheshwari R; Department of Materials Science and Engineering, University of Delaware, 201 DuPont Hall, Newark, Delaware 19716, USA.

Macromol Biosci ; 10(1): 68-81, 2010 Jan 11.

Article in En | MEDLINE | ID: mdl-19780061

Subject(s)

Cholera Toxin/antagonists & inhibitors; Cholera/drug therapy; Drug Design; Glycopeptides/chemistry; Peptide Fragments/chemical synthesis; Polymers/chemistry; Amino Acid Sequence; Cholera Toxin/chemistry; Cholera Toxin/metabolism; Circular Dichroism; Glycopeptides/chemical synthesis; Glycopeptides/metabolism; Molecular Sequence Data; Molecular Structure; Peptide Fragments/genetics; Peptide Fragments/metabolism; Polymers/metabolism; Static Electricity; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Polymers / Glycopeptides / Drug Design / Cholera / Cholera Toxin Type of study: Prognostic_studies Language: En Journal: Macromol Biosci Journal subject: BIOQUIMICA Year: 2010 Document type: Article Affiliation country: United States Country of publication: Germany

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