Tetrahydroquinoline sulfonamides as vasopressin 1b receptor antagonists.

Scott, Jack D; Miller, Michael W; Li, Sarah W; Lin, Sue-Ing; Vaccaro, Henry A; Hong, Liwu; Mullins, Deborra E; Guzzi, Mario; Weinstein, Jay; Hodgson, Robert A; Varty, Geoffrey B; Stamford, Andrew W; Chan, Tin-Yau; McKittrick, Brian A; Greenlee, William J; Priestley, Tony; Parker, Eric M

Scott, Jack D; Miller, Michael W; Li, Sarah W; Lin, Sue-Ing; Vaccaro, Henry A; Hong, Liwu; Mullins, Deborra E; Guzzi, Mario; Weinstein, Jay; Hodgson, Robert A; Varty, Geoffrey B; Stamford, Andrew W; Chan, Tin-Yau; McKittrick, Brian A; Greenlee, William J; Priestley, Tony; Parker, Eric M.

Affiliation

Scott JD; Department of Chemical Research, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA. jack.scott@spcorp.com

Bioorg Med Chem Lett ; 19(21): 6018-22, 2009 Nov 01.

Article in En | MEDLINE | ID: mdl-19800231

Subject(s)

Antidiuretic Agents/chemistry; Antidiuretic Hormone Receptor Antagonists; Quinolines/chemistry; Sulfonamides/chemistry; Animals; Antidiuretic Agents/chemical synthesis; Antidiuretic Agents/pharmacology; Humans; Quinolines/chemical synthesis; Quinolines/pharmacology; Rats; Receptors, Oxytocin/antagonists & inhibitors; Receptors, Oxytocin/metabolism; Receptors, Vasopressin/metabolism; Structure-Activity Relationship; Sulfonamides/chemical synthesis; Sulfonamides/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Quinolines / Sulfonamides / Antidiuretic Agents / Antidiuretic Hormone Receptor Antagonists Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United kingdom

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