Detoxification of nerve agents by a substituted beta-cyclodextrin: application of a modified biological assay.

Wille, T; Tenberken, O; Reiter, G; Müller, S; Le Provost, R; Lafont, O; Estour, F; Thiermann, H; Worek, F

Wille, T; Tenberken, O; Reiter, G; Müller, S; Le Provost, R; Lafont, O; Estour, F; Thiermann, H; Worek, F.

Affiliation

Wille T; Bundeswehr Institute of Pharmacology and Toxicology, Neuherbergstrasse 11, 80937 Munich, Germany.

Toxicology ; 265(3): 96-100, 2009 Nov 30.

Article in En | MEDLINE | ID: mdl-19800384

Subject(s)

Chemical Warfare Agents/toxicity; Cholinesterase Inhibitors/chemistry; Cholinesterase Inhibitors/pharmacology; beta-Cyclodextrins/chemistry; beta-Cyclodextrins/pharmacology; Acetylcholinesterase/metabolism; Biological Assay; Buffers; Chemical Warfare Agents/chemistry; Erythrocyte Membrane/enzymology; Humans; Hydrogen-Ion Concentration; Molecular Structure; Organophosphates/chemistry; Organophosphates/toxicity; Organophosphorus Compounds/chemistry; Organophosphorus Compounds/toxicity; Organothiophosphorus Compounds/chemistry; Organothiophosphorus Compounds/toxicity; Reference Standards; Reproducibility of Results; Sarin/chemistry; Sarin/toxicity; Time Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chemical Warfare Agents / Cholinesterase Inhibitors / Beta-Cyclodextrins Limits: Humans Language: En Journal: Toxicology Year: 2009 Document type: Article Affiliation country: Germany

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