Simultaneous determination of sulfasalazine and its metabolites sulfapyridine and N-acetylsulfapyridine in human serum by ion-pair high-performance liquid chromatography using a polymer-based column.

Buggé, C J; Gautam, S R; Parke, L E; Mason, J T; Garcia, D B

Buggé, C J; Gautam, S R; Parke, L E; Mason, J T; Garcia, D B.

Affiliation

Buggé CJ; Division of Pharmaceutical Sciences and Specialty Chemicals, Radian Corporation, Austin, TX 78720-1088.

J Pharm Sci ; 79(12): 1095-8, 1990 Dec.

Article in En | MEDLINE | ID: mdl-1981912

Subject(s)

Sulfapyridine/blood; Sulfasalazine/blood; Acetonitriles/analysis; Administration, Oral; Chromatography, High Pressure Liquid/methods; Humans; Ions; Quality Control; Sulfapyridine/analogs & derivatives; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Sulfasalazine / Sulfapyridine Limits: Humans Language: En Journal: J Pharm Sci Year: 1990 Document type: Article Country of publication: United States

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