Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.

Soh, Junichi; Okumura, Naoki; Lockwood, William W; Yamamoto, Hiromasa; Shigematsu, Hisayuki; Zhang, Wei; Chari, Raj; Shames, David S; Tang, Ximing; MacAulay, Calum; Varella-Garcia, Marileila; Vooder, Tõnu; Wistuba, Ignacio I; Lam, Stephen; Brekken, Rolf; Toyooka, Shinichi; Minna, John D; Lam, Wan L; Gazdar, Adi F

Soh, Junichi; Okumura, Naoki; Lockwood, William W; Yamamoto, Hiromasa; Shigematsu, Hisayuki; Zhang, Wei; Chari, Raj; Shames, David S; Tang, Ximing; MacAulay, Calum; Varella-Garcia, Marileila; Vooder, Tõnu; Wistuba, Ignacio I; Lam, Stephen; Brekken, Rolf; Toyooka, Shinichi; Minna, John D; Lam, Wan L; Gazdar, Adi F.

Affiliation

Soh J; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.

PLoS One ; 4(10): e7464, 2009 Oct 14.

Article in En | MEDLINE | ID: mdl-19826477

Subject(s)

Neoplasms/genetics; Oncogenes; Alleles; Cell Line, Tumor; Cloning, Molecular; DNA Mutational Analysis; Gene Expression Regulation, Neoplastic; Heterozygote; Humans; Models, Genetic; Mutation; Neoplasms/mortality; Neoplasms/pathology; Phenotype; Plasmids/metabolism; Polymorphism, Single Nucleotide; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oncogenes / Neoplasms Type of study: Prognostic_studies Limits: Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2009 Document type: Article Affiliation country: United States Country of publication: United States

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