Quantifying the relationship between HIV-1 susceptibility to CCR5 antagonists and virus affinity for antagonist-occupied co-receptor.

Buontempo, Peter J; Wojcik, Lisa; Buontempo, Catherine A; Ogert, Robert A; Strizki, Julie M; Howe, John A; Ralston, Robert

Buontempo, Peter J; Wojcik, Lisa; Buontempo, Catherine A; Ogert, Robert A; Strizki, Julie M; Howe, John A; Ralston, Robert.

Affiliation

Buontempo PJ; Schering-Plough Research Institute, Department of Biological Sciences- VIROLOGY, K-15-4950, Kenilworth, Building K-15-4, Mailstop 4950, 2015 Galloping Hill Road, Kenilworth, NJ 07033, USA.

Virology ; 395(2): 268-79, 2009 Dec 20.

Article in En | MEDLINE | ID: mdl-19846188

Subject(s)

Anti-HIV Agents/pharmacology; CCR5 Receptor Antagonists; Drug Resistance, Viral; HIV-1/drug effects; Allosteric Regulation; Cell Line; Dose-Response Relationship, Drug; Humans; Receptors, G-Protein-Coupled/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV-1 / Anti-HIV Agents / Drug Resistance, Viral / CCR5 Receptor Antagonists Limits: Humans Language: En Journal: Virology Year: 2009 Document type: Article Affiliation country: United States

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