Genetic fusions of heat-labile (LT) and heat-stable (ST) toxoids of porcine enterotoxigenic Escherichia coli elicit neutralizing anti-LT and anti-STa antibodies.

Zhang, Weiping; Zhang, Chengxian; Francis, David H; Fang, Ying; Knudsen, David; Nataro, James P; Robertson, Donald C

Zhang, Weiping; Zhang, Chengxian; Francis, David H; Fang, Ying; Knudsen, David; Nataro, James P; Robertson, Donald C.

Affiliation

Zhang W; Center for Infectious Disease Research & Vaccinology/Veterinary Science Department, Box 2157, South Dakota State University, Brookings, SD 57006, USA. weiping.zhang@sdstate.edu

Infect Immun ; 78(1): 316-25, 2010 Jan.

Article in En | MEDLINE | ID: mdl-19858307

Subject(s)

Antibodies, Bacterial/blood; Antibodies, Neutralizing/blood; Bacterial Toxins/genetics; Enterotoxigenic Escherichia coli/metabolism; Enterotoxins/genetics; Escherichia coli Proteins/genetics; Animals; Bacterial Vaccines/immunology; Cyclic GMP; Enterotoxigenic Escherichia coli/genetics; Enzyme-Linked Immunosorbent Assay; Escherichia coli Infections/prevention & control; Escherichia coli Infections/veterinary; Gene Expression Regulation, Bacterial; Genetic Engineering; Rabbits; Recombinant Proteins; Swine; Swine Diseases/immunology; Swine Diseases/microbiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Toxins / Escherichia coli Proteins / Enterotoxins / Enterotoxigenic Escherichia coli / Antibodies, Neutralizing / Antibodies, Bacterial Limits: Animals Language: En Journal: Infect Immun Year: 2010 Document type: Article Affiliation country: United States Country of publication: United States

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