Palovarotene, a novel retinoic acid receptor gamma agonist for the treatment of emphysema.

Hind, Matthew; Stinchcombe, Sian

Hind, Matthew; Stinchcombe, Sian.

Affiliation

Hind M; Royal Brompton Hospital, Biomedical Research Unit, Department of Respiratory Medicine, and National Heart and Lung Institute, Imperial College, Fulham Road, London, SW3 6NP, UK. m.hind@imperial.ac.uk

Curr Opin Investig Drugs ; 10(11): 1243-50, 2009 Nov.

Article in En | MEDLINE | ID: mdl-19876792

Subject(s)

Emphysema/drug therapy; Pyrazoles/pharmacology; Receptors, Retinoic Acid/agonists; Stilbenes/pharmacology; Animals; Clinical Trials as Topic; Dose-Response Relationship, Drug; Emphysema/etiology; Emphysema/physiopathology; Humans; Pulmonary Alveoli/pathology; Pyrazoles/adverse effects; Pyrazoles/therapeutic use; Signal Transduction; Smoking/adverse effects; Stilbenes/adverse effects; Stilbenes/therapeutic use; Retinoic Acid Receptor gamma

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Stilbenes / Receptors, Retinoic Acid / Emphysema Type of study: Clinical_trials / Etiology_studies Limits: Animals / Humans Language: En Journal: Curr Opin Investig Drugs Journal subject: TERAPIA POR MEDICAMENTOS Year: 2009 Document type: Article Affiliation country: United kingdom

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