[A theoretical investigation of tautomerism of adenine, purine, guanine, and cytosine].
Biofizika
; 54(5): 813-9, 2009.
Article
in Ru
| MEDLINE
| ID: mdl-19894618
ABSTRACT
The parameters of tautomeric equilibrium and stability of lactam-lactim, amino-imino, and N9H <--> N7H tautomeric forms of adenine, purine, guanine, and cytosine for isolated states have been calculated. It was found that the Ade-N9H tautomeric form is most stable; in this case the intramolecular proton transfer and tautomeric transformation Ade-N9H --> Ade-N7H can occur. The parameters of tautomeric equilibrium and stability for seven tautomeric forms of guanine were determined. For cytosine, the simultaneous existence of the amino-hydroxy, imino-oxo and valence amino-hydroxy of tautomeric forms was predicted.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Purines
/
Adenine
/
Cytosine
/
Guanine
/
Models, Chemical
Type of study:
Prognostic_studies
Language:
Ru
Journal:
Biofizika
Year:
2009
Document type:
Article