Cytotoxic effects of cardiac glycosides in colon cancer cells, alone and in combination with standard chemotherapeutic drugs.

Felth, Jenny; Rickardson, Linda; Rosén, Josefin; Wickström, Malin; Fryknäs, Mårten; Lindskog, Magnus; Bohlin, Lars; Gullbo, Joachim

Felth, Jenny; Rickardson, Linda; Rosén, Josefin; Wickström, Malin; Fryknäs, Mårten; Lindskog, Magnus; Bohlin, Lars; Gullbo, Joachim.

Affiliation

Felth J; Division of Pharmacognosy, Department of Medicinal Chemistry, Biomedical Center, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden. jenny.felth@fkog.uu.se

J Nat Prod ; 72(11): 1969-74, 2009 Nov.

Article in En | MEDLINE | ID: mdl-19894733

Subject(s)

Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacology; Antineoplastic Combined Chemotherapy Protocols/pharmacology; Camptothecin/analogs & derivatives; Camptothecin/pharmacology; Cardenolides/blood; Cardenolides/chemistry; Cardenolides/pharmacology; Colonic Neoplasms/drug therapy; Digitoxin/blood; Digitoxin/chemistry; Digitoxin/pharmacology; Digoxin/blood; Digoxin/chemistry; Digoxin/pharmacology; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Irinotecan; NF-kappa B/drug effects; Proscillaridin/blood; Proscillaridin/chemistry; Proscillaridin/pharmacology; Strophanthins/blood; Strophanthins/chemistry; Strophanthins/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Nat Prod Year: 2009 Document type: Article Affiliation country: Sweden Country of publication: United States

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