Indirect mechanisms of carcinogenesis via downregulation of PTEN function.

Leslie, Nick R; Spinelli, Laura; Tibarewal, Priyanka; Zilidis, Georgios; Weerasinghe, Nimmi; Lim, Joseph C; Maccario, Helene; Downes, C Peter

Leslie, Nick R; Spinelli, Laura; Tibarewal, Priyanka; Zilidis, Georgios; Weerasinghe, Nimmi; Lim, Joseph C; Maccario, Helene; Downes, C Peter.

Affiliation

Leslie NR; Division of Molecular Physiology, College of Life Sciences, University of Dundee, Dundee, DD1 5EH, UK.

Adv Enzyme Regul ; 50(1): 112-8, 2010.

Article in En | MEDLINE | ID: mdl-19895830

Subject(s)

Cell Transformation, Neoplastic; Down-Regulation; PTEN Phosphohydrolase/metabolism; Animals; Endosomal Sorting Complexes Required for Transport/genetics; Endosomal Sorting Complexes Required for Transport/metabolism; GTPase-Activating Proteins/genetics; GTPase-Activating Proteins/metabolism; Humans; Myosin Type V/genetics; Myosin Type V/metabolism; Nedd4 Ubiquitin Protein Ligases; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Neoplasms/genetics; Neoplasms/metabolism; PDZ Domains; PTEN Phosphohydrolase/genetics; Phosphoproteins/genetics; Phosphoproteins/metabolism; Protein Binding; Signal Transduction/physiology; Sodium-Hydrogen Exchangers/genetics; Sodium-Hydrogen Exchangers/metabolism; Tumor Suppressor Proteins/genetics; Tumor Suppressor Proteins/metabolism; Ubiquitin-Protein Ligases/genetics; Ubiquitin-Protein Ligases/metabolism; X-Linked Inhibitor of Apoptosis Protein/genetics; X-Linked Inhibitor of Apoptosis Protein/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Down-Regulation / Cell Transformation, Neoplastic / PTEN Phosphohydrolase Limits: Animals / Humans Language: En Journal: Adv Enzyme Regul Year: 2010 Document type: Article Affiliation country: United kingdom

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