VEGF-A-stimulated signalling in endothelial cells via a dual receptor tyrosine kinase system is dependent on co-ordinated trafficking and proteolysis.

Bruns, Alexander F; Bao, Leyuan; Walker, John H; Ponnambalam, Sreenivasan

Bruns, Alexander F; Bao, Leyuan; Walker, John H; Ponnambalam, Sreenivasan.

Affiliation

Bruns AF; Endothelial Cell Biology Unit, Institute of Molecular and Cellular Biology, Leeds Institute of Genetics, Health & Therapeutics Laboratories, University of Leeds, Clarendon Way, Leeds LS2 9JT, UK.

Biochem Soc Trans ; 37(Pt 6): 1193-7, 2009 Dec.

Article in En | MEDLINE | ID: mdl-19909245

Subject(s)

Endothelial Cells/metabolism; Receptor Protein-Tyrosine Kinases/metabolism; Signal Transduction/physiology; Vascular Endothelial Growth Factor A/metabolism; Animals; Golgi Apparatus/metabolism; Hydrolysis; Phosphorylation; Protein Transport/physiology; Ubiquitin/metabolism; Vascular Endothelial Growth Factor Receptor-1/metabolism; Vascular Endothelial Growth Factor Receptor-2/metabolism; rab GTP-Binding Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Receptor Protein-Tyrosine Kinases / Endothelial Cells / Vascular Endothelial Growth Factor A Type of study: Prognostic_studies Limits: Animals Language: En Journal: Biochem Soc Trans Year: 2009 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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