Long-term pioglitazone treatment augments insulin sensitivity and PKC-epsilon and PKC-theta activation in skeletal muscles in sucrose fed rats.

Marková, I; Zídek, V; Musilová, A; Simáková, M; Mlejnek, P; Kazdová, L; Pravenec, M

Marková, I; Zídek, V; Musilová, A; Simáková, M; Mlejnek, P; Kazdová, L; Pravenec, M.

Affiliation

Marková I; Institute of Physiology, Czech Academy of Sciences, Prague, Czech Republic.

Physiol Res ; 59(4): 509-516, 2010.

Article in En | MEDLINE | ID: mdl-19929130

Subject(s)

Dietary Sucrose/administration & dosage; Hypoglycemic Agents/pharmacology; Insulin Resistance; Insulin/metabolism; Isoenzymes/metabolism; Metabolic Syndrome/drug therapy; Muscle, Skeletal/drug effects; Protein Kinase C-epsilon/metabolism; Protein Kinase C/metabolism; Thiazolidinediones/pharmacology; Animals; Animals, Congenic; Blood Glucose/metabolism; CD36 Antigens/genetics; CD36 Antigens/metabolism; Dietary Sucrose/metabolism; Disease Models, Animal; Glycogen/metabolism; Male; Metabolic Syndrome/enzymology; Metabolic Syndrome/genetics; Metabolic Syndrome/physiopathology; Muscle, Skeletal/enzymology; Muscle, Skeletal/physiopathology; Pioglitazone; Protein Kinase C-theta; Protein Transport; Rats; Rats, Inbred SHR; Time Factors; Triglycerides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Protein Kinase C / Insulin Resistance / Muscle, Skeletal / Dietary Sucrose / Metabolic Syndrome / Thiazolidinediones / Protein Kinase C-epsilon / Hypoglycemic Agents / Insulin / Isoenzymes Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Physiol Res Journal subject: FISIOLOGIA Year: 2010 Document type: Article Affiliation country: Czech Republic Country of publication: Czech Republic

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